TEIDe Consortium
Bridging scientific research and primary care to support personalized, scalable prevention strategies based on physical exercise.
Early prevention
Personalization
Real-world application
Patient and Public Involvement
What is TEIDe
A European project for
dementia prevention
TEIDe – Tailored Exercise Interventions for Dementia prEvention – was created to bridge the gap between robust research evidence on the role of exercise in cognitive health and its practical use in primary healthcare.
The project brings together predictive medicine, precision exercise, mechanistic research and clinical application to develop prevention strategies that can identify risk earlier, tailor exercise to individual characteristics, understand why exercise may protect cognitive health, and test whether these approaches can work in real-world primary care.
The challenge
Turning evidence into
effective prevention
Dementia is a major cause of disability in later life, yet prevention strategies are still difficult to translate into routine care. TEIDe addresses a clear opportunity: use existing large-scale data and exercise trials to identify who may be at risk, determine what type and dose of exercise may work best for different people, and turn this evidence into practical pathways for primary healthcare.
Our vision
TEIDe aims to make dementia prevention earlier, more personalized and more implementable by connecting scientific evidence on exercise and cognitive ageing with tools and workflows designed for primary care.
The approach
The four pillars
of TEIDe
The project is built around four integrated scientific pillars, designed to move from prediction to personalization, understanding and real-world implementation.
Predictive medicine
Develop and validate risk scores for all-cause and cause-specific dementia that can support earlier identification of people at risk in primary healthcare.
01.
Precision medicine
Identify the types and doses of exercise most likely to support cognitive health according to individual characteristics such as sex/gender, age, education and cognitive or functional status.
02.
Mechanistic approach
Investigate how different forms of exercise may influence cognition through cellular and molecular pathways, brain structure and function, and behavioural mechanisms.
03.
Clinical application
Test whether a holistic prevention pathway – risk screening, tailored exercise prescription and in-person exercise intervention – is feasible within primary healthcare.
04.
An integrated pathway linking scientific research and clinical practice.
TEIDe CONSORTIUM
The Consortium
An international
collaboration
TEIDe brings together nine partners across Europe and North America, with institutions from Spain, Norway, Germany, Italy, Slovakia, Romania, the United States and Canada. Together, the network connects academia, primary healthcare, technology, patient advocacy and stakeholder engagement across eight countries.
International collaborations: Canada and the United States
Scientific coordination of the project: Spain
Partner countries: Germany, Italy, Norway, Romania, Slovakia
09
Consortium partners
08
Countries involved
08
Work Packages across the project
The partners
A network of
complementary expertise
Each TEIDe partner contributes a distinct capability: scientific coordination and exercise neuroscience; epidemiology and risk prediction; precision exercise; mechanistic and biomarker research; primary healthcare implementation; data science and artificial intelligence; and patient and public involvement, communication and dissemination. The two North American collaborators add expertise in exercise trials, neuroimaging, cognitive ageing, data analysis and knowledge translation.
TEIDe For…
Reaching
beyond Research
TEIDe is designed for people at risk of cognitive decline, families and caregivers, patient associations, healthcare professionals and systems, exercise professionals, researchers and policymakers. Their perspectives help ensure that the project’s outputs are scientifically sound, practically relevant and socially meaningful.
For People at Risk
For Caregivers
For Patient Associations
For Healthcare Professionals
For Healthcare Systems
For Researchers
Research & Innovation
Innovation & evidence
for prevention
TEIDe draws on data, clinical studies, and scientific evidence to support exercise-based approaches to preventing cognitive decline.
Discover Research & Innovation
Research & Innovation
Innovation & evidence
for prevention